최준호

서울 자연과학대학 생명과학과 교수이다.

학력

• 2003.04 - 2007.02, The University of Sydney, Majored in Biochemistry, Bachelor of Science
• 2007.03 - 2009.02, 고려대학교 생명고학과, 분자세포생물학전공, 이학석사
• 2009.03 - 2013.02, 고려대학교 생명공학과, 분자생물학전공, 이학박사

경력

• 2013.03 - 2013.10, 고려대학교 생명과학과, 박사후 연구원 (Advisor: Yoon Ki Kim)
• 2013.11 - 2014.05, 고려대학교 생명과학과, 연구교수 (Advisor: Yoon Ki Kim)
• 2014.07 - 2019.01, Boston Children’s Hospital / Harvard Medical School, Postdoctoral Fellow (Advisor: Richard I. Gregory)

연구관심분야

• RNA 후성유전체학 (Epitranscriptomics)
• RNA modification을 통한 mRNA 안정성 조절 및 단백질 발현 조절 연구
• RNA modification을 통한 종양형성 (Tumorigenesis) 연구
• 배아줄기세포 (Mouse Embryonic Stem Cell) 에서의 유전자 발현 조절 연구

주요논문

1. mRNA circularization by METTL3-eIF3h enhances translation and promotes oncogenesis. Nature, 561(7724):556-560, 2018
2. The m6A Methyltransferase METTL3 Promotes Translation in Human Cancer Cells. Mol cell, 62(3):335-45, 2016
3. eIF4AIII enhances translation of nuclear cap-binding complex-bound mRNAs by promoting disruption of secondary structures in 5'UTR. Proc Natl Acad Sci U S A, 111(43):E4577-86, 2014
4. The mRNP remodeling mediated by UPF1 promotes rapid degradation of replication-dependent histone mRNA. Nucleic Acids Research, 42(14): 9334-49, 2014
5. Rapid degradation of replication-dependent histone mRNAs largely occurs on mRNAs bound by nuclear cap-binding proteins 80 and 20. Nucleic Acids Research, 41(2):1307-18, 2013

수상

• 2013, Excellent Research Award by Korea University
• 2012, Excellent Research Award by Korea University
• 2011, Excellent Research Award by Korea University
• 2011, Excellent Poster Award by KSCB
• 2010, Excellent Research Award by KSMCB - The RNA Society of Korea
• 2010, Excellent Poster Award by KSCB
• 2009, Fellowship from Seoul
• 2007, Fellowship from KRF (Korea Research Foundation)