이진원

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서울캠퍼스 자연과학대학 생명과학과 교수이다.

학력

  • 1989.3 - 1995.2, 서울대학교 미생물학과 학사
  • 1995.3 - 1997.2, 서울대학교 미생물학과 석사
  • 1997.3 - 2002.8, 서울대학교 생명과학부 박사

연구실적

  • Conversion of Bacillus subtilis OhrR from a 1-Cys to a 2-Cys peroxide sensor .J Bacteriol. 2008 190(17):5738-45
  • A complex thiolate switch regulates the Bacillus subtilis organic peroxide sensor OhrR. Proc Natl Acad Sci U S A. 2007 104(21):8743-8
  • The PerR transcription factor senses H2O2 by metal-catalysed histidine oxidation. Nature 2006 440:363?367.
  • Biochemical characterization of the structural Zn2+ site in the Bacillus subtilis peroxide sensor PerR. J Biol Chem.2006 281(33):23567-78
  • Crystal structure of nickel-containing superoxide dismutase reveals another type of active site. Proc Natl Acad Sci U S A. 2004 101(23):8569-74.
  • Phosphorylation of p27Kip1 on T157 interferes with its association with importin alpha during G1 phase and prevents nuclear re-entry.Shin, I., Rotty, J., Wu, F. and Arteaga, C.L. J. Biol. Chem. 280:6055-6063 (2005)
  • Pro-apoptotic activity of cell-permeable anti-Akt single chain antibodies.Shin, I., Edl, J., Biswas, S., Lin, C., Mernaugh, R.L. and Arteaga, C.L. Cancer Res. 65:2815-2823 (2005)
  • Down-regulation of Notch-dependent transcription by Akt in vitro. Song J, Park S, Kim M, Shin I. FEBS Lett. 28;582(12):1693-9 (2008)
  • Akt stabilizes estrogen receptor alpha with the concomitant reduction in its transcriptional activity. Park S, Song J, Joe CO, Shin I. Cell Signal. Jul;20(7):1368-74 (2008)

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