Sang-Cheol Bae

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Profile

  • 2019-present Director, Hanyang University Institute for Rheumatology Research, Seoul, Korea
  • 2018-present Editorial Board, Annals of Rheumatic Diseases
  • 2018-present Vice President, Korean Academy of Medical Sciences
  • 2018-present Full member, Korean Academy of Science and Technology
  • 2016-present Full member, APLC (Asia Pacific Lupus Collaboration)
  • 2016-present President, Korean Society of SLE Research
  • 2011-present Full member, National Academy of Medicine of Korea
  • 2008-2015 Clinical Research Center for Rheumatoid Arthritis by Ministry of Health and Welfare, Korea (PI, Director)
  • 2006-2007 Presidential Medical R&D advisory committee member
  • 2005-2019 Director, Hanyang University Hospital for Rheumatic Diseases, Seoul, Korea
  • 1998-present Full member, SLICC (Systemic Lupus International Collaborating Clinics)
  • 1997-1998 Ad hoc Committee on Neuropsychiatric SLE nomenclature (co-chair)
  • 1996-1998 Research Fellow and Instructor, Brigham & Women’s Hospital, Harvard Medical School, Boston, MA, USA
  • 1993-present Professor in Internal Medicine, Rheumatology, Hanyang University, Seoul, Korea
  • 2012-present Hanyang University Distinguished Professor, Seoul, Korea
  • 1993-present Professor in Internal Medicine, Rheumatology, Hanyang University, Seoul, Korea
  • 1996-1998 MPH, School of Public Health, Harvard University, Boston, MA, USA
  • 1985-1993 PhD (Medicine), Hanyang University, Seoul, Korea
  • 1978-1984 MD, College of Medicine, Hanyang University, Seoul, Korea

Professor Sang-Cheol Bae acquired his MD in 1984, and subsequently a PhD in 1993, from the Hanyang University, Seoul, Korea. From 1996 to 1998, he worked as a rheumatology research fellow and instructor at the Brigham and Women’s Hospital, Harvard Medical School, Boston, USA. In 1998, he also obtained a Master of Public Health degree from the Harvard School of Public Health, Boston, USA. Throughout his illustrious career, he has been honoured with numerous academic awards, including the 2008 Distinguished Clinical Investigator Award by the Asia Pacific League of Associations for Rheumatology, 2010 Hanmi Proud Doctor Award by the Korean Medical Association, 2011 Korean Rheumatology Academic Award by the Korean College of Rheumatology, 2012 Hanyang University Distinguished Scholar Professor award, 2016 Minister of Health & Welfare Award, 2017 National R&D Excellence Award by Minister of Science and ICT, 2018 Wunsch Medical Award by the Korean Academy of Medical Sciences, and 2019 Paiknam Distinguished Scholar Professor award by Hanyang University.

Research Topics

  • Systemic Lupus Erythematosus [SLE] and Rheumatoid Arthritis [RA]
  • Clinical Epidemiology (including clinimetrics, clinical trials and innovative treatment development, clinical and pharmaco-economics, and outcomes research)
  • Genetic Epidemiology including drug discovery and repurposing
  • Precision Medicine

Prof Bae’s research has the overall theme of understanding clinical, environmental & genetic factors associated with SLE and RA and their individual prognosis and drug response prediction for the precision medicine. For this purpose, as one of the most prominent clinician and researchers in Asia in this field, he has established largest Korean SLE & RA cohorts, solved clinically important questions, and identified clinical predictors and dozens of common genetic variants and epidemiologic factors conferring risk of the diseases using the advanced methodology like GWAS, NGS, immunochip, and HLA imputation for multiple ancestral populations. With these studies, he has also discovered novel biologic insights and therapeutic targets which implicate a potential guiding role of human SLE/RA genetics data in drug discovery and repurposing. In addition, he has already started to go beyond genetics and conduct thorough integrated analyses with epigenetics, transcriptomics, proteomics and more. He has successfully administered and participated in many multinational and multicenter projects as a principal investigator and co-investigator and he is always well aware of the factors needed for a successful research project which he will carry out.

Papers

He has published ~700 articles on these topics in national and international peer-reviewed journals including, New England Journal of Medicine, Nature, Nature Genetics, Nature communications, American Journal of Human Genetics, PLoS genetics, Annals of the Rheumatic Diseases, Arthritis and Rheumatology, Human Molecular Genetics, and Rheumatology, to name a few. Selected articles are as follows.

  • “Smoking, the HLA-DRB1 shared epitope and ACPA fine-specificity in Koreans with rheumatoid arthritis: evidence for more than one pathogenic pathway linking smoking to disease”, Ann Rheum Dis, 2014 https://ard.bmj.com/content/73/4/741.short

Contact Information

  • E-mail : scbae@hanyang.ac.kr